Recombinant Mouse BTN1A1/Butyrophilin Subfamily 1 Member A1,BR

产品属性 Product Attributes

基本信息

别名： Butyrophilin subfamily 1 member A1;BTN;BTN1A1;butyrophilin;Btn1a1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Mouse Butyrophilin subfamily 1 member A1(BTN1A1) is a type I transmembrane glycoprotein which is a member of the Ig superfamily.The BTN1A1 ECD displays two predicted IgV and IgC domains as do B7 and Skint proteins which interact with other Ig superfamily members.BTN1A1 binds to xanthine oxidoreductase (XOR).This interaction stabilizes the association of XOR with the milk fat globule membrane and appears to be essential in the control of milk fat globule secretion.In vitro，BTN1A1 inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies，T-cell metabolism and IL-2 and IFN-γ secretion.Furthermore，in vivo，BTN1A1 has a protective effect against the development of experimental autoimmune encephalomyelitis (EAE).Because butyrophilins are structurally related to B7 proteins and are functionally implicated in immune regulation，they may represent an emerging family of costimulatory/inhibitory molecules.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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