Recombinant Mouse CD5 antigen-like/CD5L,BR

产品属性 Product Attributes

基本信息

别名： CD5 antigen-like;Apoptosis inhibitor expressed by macrophages;Apoptosis inhibitory 6;CT-2;SP-alpha;Cd5l;Aim;Api6
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： CD5L，also known as CD5 antigen-like，is secreted protein which mainly expressed by macrophages in lymphoid and inflammed tissues and regulates mechanisms in inflammatory responses，such as infection or atherosclerosis.It is able to inhibit lipid droplet size in adipocytes.CD5L acts as a key regulator of metabolic switch in T-helper Th17 cells.It is Participates in obesity-associated autoimmunity via its association with IgM，interfering with the binding of IgM to Fcalpha/mu receptor and enhancing the development of long-lived plasma cells that produce high-affinity IgG autoantibodies.It also acts as an inhibitor of apoptosis in macrophages: promotes macrophage survival from the apoptotic effects of oxidized lipids in case of atherosclerosis.It is involved in early response to microbial infection against various pathogens by acting as a pattern recognition receptor and by promoting autophagy.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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