Recombinant Human ICOS/AILIM/CD278/Inducible T-cell costimulator,BR

产品属性 Product Attributes

基本信息

别名： Inducible T-cell costimulator;activation-inducible lymphocyte immunomediatory molecule;CD278;AILIM;CVID1;ICOS;
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Inducible T-cell costimulator，also known as activation-inducible lymphocyte immunomediatory molecule，CD278，AILIM，CVID1 and ICOS，belongs to the CD28 and CTLA4 cell surface receptor family.ICOS contains one Ig-like V-type domain and exsits as a homodimer with disulfide-linked.ICOS is highly expressed on tonsillar T-cellsand can be induced by PMA and ionomycin，ICOS plays an important role in cell-cell signaling，immune responses，and regulation of cell proliferation.Defects in ICOS are the cause of immunodeficiency common variable type 1，which is a primary immunodeficiency characterized by antibody deficiency，hypogammaglobulinemia，recurrent bacterial infections and an inability to mount an antibody response to antige
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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