Recombinant Mouse LTBR/TNFRSF3,BR

产品属性 Product Attributes

基本信息

别名： Tumor necrosis factor receptor superfamily member 3;Lymphotoxin-beta receptor;Ltbr;Tnfcr;Tnfrsf3
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： It is a single-pass type I membrane protein and contains 4 TNFR-Cys repeats.The protein is a member of the tumor necrosis factor (TNF) family of receptors.It is expressed on the surface of most cell types，including cells of epithelial and myeloid lineages，but not on T and B lymphocytes.The protein is the receptor for the heterotrimeric lymphotoxin containing LTA and LTB，and for TNFS14/LIGHT.It promotes apoptosis via TRAF3 and TRAF5 and may play a role in the development of lymphoid organs.The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and transformed cells.Activation of the encoded protein can trigger apoptosis.Not only does the TNFRSF3 help trigger apoptosis，it can lead to the release of the cytokine interleukin 8.Overexpression of TNFRSF3 in Human Cells cells increases IL-8 promoter activity and leads to IL-8 release.TNFRSF3 is also essential for development and organization of the secondary lymphoid organs and chemokine release.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/μg(1 EU/μg)as determined by LAL test.

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