Recombinant Human Protein phosphatase 1 regulatory subunit 14A/CPI-17,BR

产品属性 Product Attributes

基本信息

别名： Protein Phosphatase 1 Regulatory Subunit 14A;17 kDa PKC-Potentiated Inhibitory Protein of PP1;Protein Kinase C-Potentiated Inhibitor Protein of 17 kDa;CPI-17;PPP1R14A;CPI17;PPP1INL
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 0.2mM EDTA, 1mM DTT, 10% Glycerol, pH 8.0.
纯度: ≥85% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Protein Phosphatase 1 Regulatory Subunit 14A (PPP1R14A) belongs to the PP1 inhibitor family.PPP1R14A is mapped to chromosome 19q13.13-q13.2.PPP1R14A binds directly to protein kinase C and casein kinase I.Meantime，PPP1R14A is a phosphorylation-dependent inhibitor of smooth muscle myosin phosphatase.PPP1R14A is the inhibitor of PPP1CA.When phosphorylated，PPP1R14A has over 1000-fold higher inhibitory activity，creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.In addition，inhibition of PPP1R14A also enhances contraction of smooth muscle in the absence of increment of intracellular Ca2+ concentration.
来源： E.coli

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

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