Recombinant Human STING/Stimulator of Interferon Genes Protein/Sting/TMEM173,BR

产品属性 Product Attributes

基本信息

别名： Stimulator of interferon genes protein;TMEM173;Mediator of IRF3 activation;sting;
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Stimulator of Interferon Gene(Sting，TMEM173) belongs to the TMEM173 family.STING is 379 amino acids (aa) in length.It contains an N-terminal cytoplasmic region (aa 1-20)，four transmembrane segments (aa 21-173)，and a C-terminal cytoplasmic domain (aa 174-379).It ubiquitously expressed in skin endothelial cells，alveolar type 2 pneumocytes，bronchial epithelium and alveolar macrophagesand.Its subunit structure associated with the MHC-II complex and Interacts with DDX58/RIG-I，MAVS and SSR2，RNF5 and TRIM56 along with TBK1.This type of protein often uses as facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon.
来源： E.coli

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

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