Recombinant Human SPINK1/Pancreatic secretory trypsin inhibitor/PST1,BR

产品属性 Product Attributes

基本信息

别名： Pancreatic Secretory Trypsin Inhibitor;Serine Protease Inhibitor Kazal-Type 1;Tumor-Associated Trypsin Inhibitor;TATI;SPINK1;PSTI
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, 2mM CaCl2, 1mM DTT, 0.05% Brij35, 10% Glycerol, pH 6.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Serine Protease Inhibitor Kazal-Type 1 (SPINK1) is a trypsin inhibitor that prevent the trypsin-catalyzed premature activation of zymogens within the pancreas.Defects in SPINK1 are a cause of pancreatitis (PCTT).A disease characterized by the presence of calculi in pancreatic ducts.It causes severe abdominal pain attacks.Defects in SPINK1 are the cause of susceptibility to tropical calcific pancreatitis (TCP).Recombinant SPINK1 protein (rSPINK1) stimulated cell proliferation in benign RWPE as well as cancerous prostate cells.The research result indicated that the potential of SPINK1 as an extracellular therapeutic target in prostate cancer.In contrast，knockdown of SPINK1 in 22RV1 cells inhibited cell proliferation，cell invasion，and tumor growth in xenograft assays.
来源： Human Cells

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。