Recombinant Human Carboxypeptidase B2/CPB2,BR

产品属性 Product Attributes

基本信息

别名： Carboxypeptidase B2;Carboxypeptidase U;CPU;Plasma Carboxypeptidase B;pCPB;Thrombin-Activable Fibrinolysis Inhibitor;TAFI;CPB2
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl,150mM NaCl,1mM ZnCl2,10%Glycerol, pH7.5.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Carboxypeptidase B2 (CPB2) is a secreted enzyme that belongs to the peptidase M14 family.CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen by the liver and circulates in the plasma as a plasminogen-bound zymogen.CPB2 cleaves C-terminal arginine or lysine residues from biologically active peptides，such as kinins or anaphylatoxins，in the circulation regulating their activities.CPB2 also down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin.CPB2 exhibits carboxypeptidase activity when it is activated by proteolysis at residue Arg92 of the thrombin/thrombomodulin complex.Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen.
来源： Human Cells

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

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