Recombinant Human Calnexin/IP90/CANX,BR

产品属性 Product Attributes

基本信息

别名： Calnexin;IP90;Major Histocompatibility Complex Class I Antigen-Binding Protein p88;p90;CANX
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 2mM CaCl2, 10% Glycerol, pH 7.5.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Calnexin/CANX is a single-pass type I membrane protein which belongs to the calreticulin family.It consists of a large N-terminal calcium-binding lumenal domain，a single transmembrane helix and a short (90 residues)，acidic cytoplasmic tail.The function of calnexin is to retain unfolded or unassembled N-linked glycoproteins in the endoplasmic reticulum.Calnexin is a calcium-binding protein that interacts briefly with newly synthesized glycoproteins in the endoplasmic reticulum.Calnexin may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits.Calnexin seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.Calnexin dwindles with aging and might contribute to a cytoprotection in an array of human age-related diseases.
来源： Human Cells

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

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