Recombinant Human Disks large homolog 4/DLG4/PSD95,BR

产品属性 Product Attributes

基本信息

别名： Disks large homolog 4;Postsynaptic density protein 95;PSD-95;Synapse-associated protein 90;SAP-90;SAP90;PSD95;DLG4
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥90% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Disks large homolog 4(DLG4) is a cell membrane protein and it is a member of the membrane-associated guanylate kinase (MAGUK) family.The protein contains 1 guanylate kinase-like domain，3 PDZ (DHR) domains and 1 SH3 domain.With PSD-93 it is recruited into the same NMDA receptor and potassium channel clusters.These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors，ion channels，and associated signaling proteins.DLG4 is the best studied member of the MAGUK-family of PDZ domain-containing proteins.Like all MAGUK-family proteins，its basic structure includes three PDZ domains，an SH3 domain，and a guanylate kinase-like domain (GK) connected by disordered linker regions.It is almost exclusively located in the post synaptic density of neurons，and is involved in anchoring synaptic proteins.Its direct and indirect binding partners include neuroligin，NMDA receptors，AMPA receptors，and potassium channels.
来源： E.coli

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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