Recombinant Human IL-22/Interleukin-22,BR

产品属性 Product Attributes

基本信息

别名： Interleukin-22;IL-22;Cytokine Zcyto18;IL-10-related T-cell-derived-inducible factor;IL-TIF;IL22
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Interleukin-22(IL-22) is a member of a group of the IL-10 family，a class of potent mediators of cellular inflammatory responses.IL-22 is produced by activated DC and T cells.IL-22 and IL-10 receptor chains play a role in cellular targeting and signal transduction.It can initiate and regulate innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells.IL-22 along with IL-17 likely plays a role in the coordinated response of both adaptive and innate immune systems.IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10.Biological activity of IL-22 is initiated by binding to a cell-surface complex consisting of IL-22R1 and IL-10R2 receptor chains.IL-22 biological activity is further regulated by interactions with a soluble binding protein，IL-22BP.IL-22BP and an extracellular region of IL-22R1 share sequence similarity.In some cases，the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by cytokine IL-17A.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

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