Recombinant Human Siglec-15/Sialic acid-binding Ig-like lectin 15/CD33 antigen-like 3/CD33L3,BR

产品属性 Product Attributes

基本信息

别名： Sialic acid-binding Ig-like lectin 15;Siglec-15;CD33 antigen-like 3;CD33L3
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, 150mMNacl, 0.3%chaps, 5% Trehalose, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Human Siglec-15 is a transmembrane glycoprotein in the Siglec family.Siglecs are type I transmembrane proteins where the NH3+-terminus is in the extracellular space and the COO--terminus is cytosolic.Each Siglec contains an N-terminal V-type immunoglobulin domain (Ig domain) which acts as the binding receptor for sialic acid.These lectins are placed into the group of I-type lectins because the lectin domain is an immunoglobulin fold.All Siglecs are extended from the cell surface by C2-type Ig domains which have no binding activity.Siglecs differ in the number of these C2-type domains.Human Siglec-15 consists of a 244 amino acid (aa) extracellular domain (ECD) with two Ig-like domains，a 21 aa transmembrane segment，and a 44 aa cytoplasmic domain.Siglec-15 function is important for osteoclast formation and TRANCE/RANK Ligand signaling in osteoclasts.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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