Recombinant Human Corticotropin-releasing factor-binding protein/CRHBP,BR

产品属性 Product Attributes

基本信息

别名： Corticotropin-Releasing Factor-Binding Protein;CRF-BP;CRF-Binding Protein;Corticotropin-Releasing Hormone-Binding Protein;CRH-BP;CRHBP;CRFBP
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 150mm NaCl, pH 7.5.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Corticotropin-Releasing Factor-Binding Protein (CRHBP) is a 37 kDa secreted glycoprotein that binds both CRH and urocortin in a 42 kDa extracellular complex.The molecule is approximately 300 amino acids in length and demonstrates five intrachain disulfide bonds.Difference between CRHBP from different species exist，human CRHBP is found in plasma while rodent and sheep CRHBP is limited to neuroendocrine tissues.CRHBP may inactivate CRH and may prevent inappropriate pituitary-adrenal stimulation in pregnancy.CRHBP is presumed to either sequester CRH，rendering it unavailable to cells or transport it to target tissues.Although CRF-BP concentration in the human peripheral circulation is normally low，it increases throughout pregnancy and fall back rapidly after parturition.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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