Recombinant Human CCL16/HCC-4,BR

产品属性 Product Attributes

基本信息

别名： C-C Motif Chemokine 16;Chemokine CC-4;HCC-4;Chemokine LEC;IL-10-Inducible Chemokine;LCC-1;Liver-Expressed Chemokine;Lymphocyte and Monocyte Chemoattractant;LMC;Monotactin-1;MTN-1;NCC-4;Small-Inducible Cytokine A16;CCL16;ILINCK;NCC4;SCYA16
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： CCL16 is a member of CC chemokine family.CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein.CCL16 is distantly related to other CC chemokines，showing less than 30% sequence identity.CCL16 elicits its effects on cells by interacting with cell surface chemokine receptors such as CCR1，CCR2，CCR5 and CCR8.Recombinant CCL16 has been shown to chemoattract human monocytes and THP1 cells but not resting lymphocytes nor neutrophils.CCL16 has potent myelosuppressive activity，suppresses proliferation of myeloid progenitor cells.CCL16ninduces a calcium flux in THP1 cells that can be desensitized by prior exposure to RANTES，suggesting that CCL16 and RANTES share the same receptor in THP1 cells.
来源： E.coli

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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