Recombinant Human CDK2,BR

产品属性 Product Attributes

基本信息

别名： Cyclin-Dependent Kinase 2;Cell Division Protein Kinase 2;p33 Protein Kinase;CDK2;CDKN2
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, 1mM DTT, 40% Glycerol, pH 8.0.
纯度: ≥90% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Cyclin-dependent kinase 2 (CDK2) belongs to the cyclin-dependent kinase of Ser/Thr protein kinase.CDK2 acts as a catalytic subunit of the cyclin dependent kinase complex，whose activity is restricted to the G1-S phage of the cell cycle，it is essential for the G1/S transition.The kinase activity of CDK2 can be regulated by the association with a cyclin subunit，its phosphorylation state and CDK inhibitors.The activation of the CDK2/cyclin complex requires the phosphorylation of Thr160 and the dephosphorylation of Try14 and Tyr15.The inhibition of CDK2-cyclin complex can also be attributed to association with p27Kip1 and p21Waf1/Cip1.The activation of CDK2 has been shown to be necessary for apoptosis of quiescent cells，such as neurons，thymocytes and endothelial cells.
来源： E.coli

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

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