Recombinant Human HSPB11/PP25,BR

产品属性 Product Attributes

基本信息

别名： Heat Shock Protein Beta-11;Hspb11;Placental Protein 25;PP25;HSPB11;C1orf41
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 2mM DTT, 10% Glycerol, pH 8.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Heat Shock Protein β-11 (HSPB11) is a stress-responsive protein that is required to deal with proteotoxic stresses.HSPB11 is composed of an IFT complex B composed of IFT88，IFT57，TRAF3IP1，IFT52，IFT27，HSPB11 and IFT20 and is detected in placenta.HSPB11 has beeb shown to form oligomeric complexes and prevent the aggregation of in vitro denaturated aldolase and glyceraldehyde-3-phosphate dehydrogenase in accordance with the chaperone model of HSPB1 and HSPB5.HSPB11 overexpression protected against etoposide-induced cell death that correlated with a decreased release of mitochondrial Cytochrome C into the cytosol.Inhibition of HSP90 function completely abrogated the protective effect of HSPB11.This data suggests that at least in the case of HSPB11，interaction with other chaperone machines besides HSPA1A may contribute to functional specificity and cellular functioning.
来源： E.coli

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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