Recombinant Human QAPRTase/QPRT,BR

产品属性 Product Attributes

基本信息

别名： Nicotinate-Nucleotide Pyrophosphorylase [Carboxylating];Quinolinate Phosphoribosyltransferase [Decarboxylating];QAPRTase;QPRTase;QPRT
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family.QPRT plays an improtant role in catabolism of quinolinate which acts as a potent endogenous exitotoxin to neurons.In addition，QPRT serves as an an intermediate in the Tryptophan-Nicotinamide Adenine Dinucleotide pathway.QPRT participates in some pathways including Cofactor biosynthesis，NAD(+) biosynthesis and the Nicotinate D-Ribonucleotide from Quinolinate.In addition，QPRT is involved in the catabolism of Quinolinic Acid (QA).The activity toward QA is slightly repressed by phosphoribosylpyrophosphate (PRPP) in both a competitive and a non-competitive manner.
来源： E.coli

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

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