Recombinant Human B4GALT1,BR

产品属性 Product Attributes

基本信息

别名： 1,4- galactosyltransferase,polypeptide 1;B4GalT1;B4GAL-T1;beta-1,4-galactosyltransferase 1;Beta-1,4-GalTase 1;beta4Gal-T1;betaGlcNAc beta;CDG2D;GT1;GTB
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Beta1，4-Galactosyltransferase-I (B4GALT1)，one of seven beta1，4-galactosyltransferases，is an enzyme commonly found in the trans-Golgi complex that adds galactose to oligosaccharides.By sequence similarity，the beta 4GalTs form four groups: beta 4GalT1 and beta 4GalT2，beta 4GalT3 and beta 4GalT4，beta 4GalT5 and beta 4GalT6，and beta 4GalT7.beta 4GalT1 is unique among the seven enzymes because it can be expressed either as membrane associated form or secreted form.The secreted form is restricted to lactating mammary tissues where the enzyme forms a heterodimer with alpha -lactalbumin to catalyze the synthesis of lactose.The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.The cell surface form functions as a recognition molecule during a variety of cell to cell and cell to matrix interactions，as those occurring during development and egg fertilization，by binding to specific oligosaccharide ligands on opposing cells or in the extracellular matrix.Defects in beta 4GalT1 are the cause of congenital disorder of glycosylation type 2D (CDG2D).
来源： Human Cells

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

暂无数据

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。