Recombinant Human Carboxylesterase 1/CES1,BR

产品属性 Product Attributes

基本信息

别名： Liver Carboxylesterase 1;Acyl-Coenzyme A:Cholesterol Acyltransferase;ACAT;Brain Carboxylesterase hBr1;Carboxylesterase 1;CE-1;hCE-1;Cocaine Carboxylesterase;Egasyn;HMSE;Methylumbelliferyl-Acetate Deacetylase 1;Monocyte/Macrophage Serine Esterase;Retinyl Ester Hydrolase;REH;Serine Esterase 1;Triacylglycerol Hydrolase;TGH;CES1;CES2;SES1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM HAc-NaAc, 150mM NaCl, pH 4.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Carboxylesterase 1 (CES1) is a member of a large family of carboxylesterases that are responsible for the hydrolysis of ester and amide bonds.These enzymes have broad substrate specificity ranging from small molecule esters such as phenylester to long chain fatty acid esters and thioesters.They are major determinants of the pharmacokinetic behavior of most therapeutic agents containing an ester or amide bond.CES1 shares the serine hydrolase fold observed in other esterases.CES1 hydrolyzes aromatic and aliphatic esters，but has no catalytic activity toward amides or a fatty acyl-CoA ester.CES1 participates in detoxification of drugs such as cocaine and heroin in serum and liver.It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds.
来源： Human Cells

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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