Recombinant Human Insulysin/IDE,BR

产品属性 Product Attributes

基本信息

别名： Insulin-Degrading Enzyme;Abeta-Degrading Protease;Insulin Protease;Insulinase;Insulysin;IDE
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,0.05%Brij35,10%Glycerol,pH7.5.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family.IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence.IDE plays a role in the cellular breakdown of insulin，IAPP，glucagon，bradykinin，kallidin，and other peptides，and thereby plays a role in intercellular peptide signaling.IDE degrades amyloid formed by APP and IAPP.IDE may participate in the degradation and clearance of naturally secreted amyloid β-protein by neurons and microglia.IDE，which migrates at 110 kDa during gel electrophoresis under denaturing conditions，has since been shown to have additional substrates，including the signaling peptides glucagon，TGF α and β-endorphin.
来源： Human Cells

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。