Recombinant Human RHEB/RHEB2,BR

产品属性 Product Attributes

基本信息

别名： GTP-Binding Protein Rheb;Ras Homolog Enriched in Brain;RHEB;RHEB2
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 10mM GSH, pH 8.0.
纯度: ≥85% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： GTP-Binding Protein Rheb (RHEB) is a member of the small GTPase superfamily and encodes a lipid-anchored，cell membrane protein with five repeats of the RAS-related GTP-binding region.Highest levels of RHEB can be found in the skeletal and cardiac muscle，and it is vital in the regulation of growth and cell cycle progression due to its role in the Insulin/TOR/S6K signaling pathway.RHEB stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling，and it activates the protein kinase activity of mTORC1.RHEB has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form，farnesylation of the protein is required for this activity.
来源： E.coli

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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