Recombinant Human IL-17A & IL17F Heterodimer,BR

产品属性 Product Attributes

基本信息

别名： IL-17A/F Heterodimer;IL-17A&IL-17F Heterodimer
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, pH 7.4.
纯度: ≥90% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： The IL-17 family include IL-17A，IL-17B，IL-17C，IL-17D，IL-17E (also called IL-25)，and IL-17F.The family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus.All members of the IL-17 family have a similar protein structure，with four highly conserved cysteine residues critical to their 3-dimensional shape，yet they have no sequence similarity to any other known cytokines.IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation.IL-17 is induced by IL-15 and IL-23，mainly in activated CD4+ T cells distinct from Th1 or Th2 cells.IL-17F is the most homologous to IL-17，but is induced only by IL-23 in activated monocytes.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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