Recombinant Mouse Kallikrein 7/KLK7,BR

产品属性 Product Attributes

基本信息

别名： Kallikrein-7;Klk7;Serine protease 6;Stratum corneum chymotryptic enzyme;Thymopsin;kallikrein-related peptidase 7;PRSS6;SCCEkallikrein-7
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM HEPES,150mM NaCl,pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Kallikrein7，also named as stratum corneum chymotryptic enzyme (SCCE)，is a secreted protein of the Kallikrein-related peptidase (KLK) family.This family contains fifteen homologous secreted serine endopeptidases and plays a significant role in various physiological processes，including skin desquamation，semen liquefaction，neural plasticity，and body fluid homeostasis.In skin KLK5，KLK 7 and KLK14 are able to degrade corneodesmosomes，which leads to desquamation of skin surface cells.KLK activation is believed to be mediated through highly organized proteolytic cascades，regulated through a series of feedback loops，inhibitors，auto-degradation and internal cleavages.Studies have shown that one potential physiological activator for KLK7 is KLK5.Along with KLK14，these three kallikreins form a proteolytic cascade in the stratum corneum.KLK7 is primarily expressed in the skin but is also detected at relatively high levels in esophagus，heart，liver，central nervous system，kidney，pancreas，mammary and salivary glands.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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