Recombin human TIA1 protein,BR

产品属性 Product Attributes

基本信息

基因名: TIA1
别名: TIA-1;WDM;nucleolysin TIA-1 isoform p40
英文名称: Recombinant human TIA1 protein
全名: cytotoxic granule-associated RNA binding protein
中文名称: 细胞毒颗粒RNA结合蛋白
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件: The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

产品信息

Swiss Prot： P31483
Gene ID： 7072
交叉反应： Human Mouse
分子量： 24kDa
区间范围： 1-214aa
背景说明： The product encoded by this gene is a member of a RNA-binding protein family and involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs).Possesses nucleolytic activity against cytotoxic lymphocyte target cells.It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets.The major granule-associated species is a 15-kDaa protein that is thought to be derived from the carboxyl terminus of the 40-kDaa product by proteolytic processing.Alternative splicing resulting in different isoforms of this gene product has been described in the literature.
应用： Immunology research
来源： E.coli

其它标识

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

产品介绍 Product Introduction

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