Recombin human CHAC1 protein,BR

产品属性 Product Attributes

基本信息

基因名: CHAC1
别名: glutathione-specific gamma-glutamylcyclotransferase 1
全名: Glutathione-specific gamma-glutamylcyclotransferase 1
英文名称: Recombinant human CHAC1 protein
中文名称: 谷胱甘肽特异性γ-谷氨酰环转移酶1
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件: The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

产品信息

Swiss Prot： Q9BUX1
Gene ID： 79094
交叉反应： Human Mouse Rat (Zebrafish)
分子量： 24kDa
区间范围： 1-222aa
背景说明： Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide.Acts specifically on glutathione, but not on other gamma-glutamyl peptides (PubMed:27913623).Glutathione depletion is an important factor for apoptosis initiation and execution.Acts as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade (PubMed:19109178).Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos (PubMed:22445366).
应用： Immunology research
来源： E.coli

其它标识

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

产品介绍 Product Introduction

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注意事项 Considerations

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