Recombin human SPIN2B protein,BR

产品属性 Product Attributes

基本信息

基因名: SPIN2B
别名: SPIN2B;SPIN-2;SPIN-2B;SPIN2_duplicate;TDRD26;dJ323P24.2;spindlin-2B
全名: spindlin family，member 2B
英文名称: Recombinant human SPIN2B protein
中文名称: spindlin家族成员2B
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件: The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

产品信息

Swiss Prot： Q9BPZ2
Gene ID： 474343
交叉反应： Human Rat
分子量： 29kDa
区间范围： 1-259aa
背景说明： Human SPIN2 expressed by 2 IL3-dependent murine myeloid cell lines was moderately antiapoptotic following IL3 removal, but it was unable to block apoptosis induced by the chemotherapy agent doxorubicin.On the contrary, SPIN2-expressing cells were more sensitive to doxorubicin-mediated cell death.Also, SPIN2 did not combat the proapoptotic effects of Fas ligand stimulation in the Jurkat human T-cell line.Deletion of the C-terminal amino acids of SPIN2 diminished its antiapoptotic activity.In the murine myeloid cells, SPIN2 overexpression increased the cell number doubling times and slowed their rate of growth.There was also an increased percentage of cells in G2/M, which was more pronounced following IL3 withdrawal.
应用： Immunology research
来源： E.coli

其它标识

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

产品介绍 Product Introduction

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。