Recombin human MORF4L1 protein,BR

产品属性 Product Attributes

基本信息

基因名: MORF4L1
别名: MORF4L1;Eaf3;FWP006;HsT17725;MEAF3;MORFRG15;MRG15;S863-6;mortality factor 4 like 1
英文名称: Recombinant human MORF4L1 protein
全名: mortality factor 4 like 1
中文名称: 死亡因子4样蛋白1
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件: The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

产品信息

Swiss Prot： Q9UBU8
Gene ID： 10933
交叉反应： Human Mouse Rat (Gorilla)
分子量： 36kDa
区间范围： 1-324aa
背景说明： Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A.This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription.This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction； tumor suppressor mediated growth arrest and replicative senescence； apoptosis； and DNA repair.The NuA4 complex ATPase and helicase activities seem to be； at least in part； contributed by the association of RUVBL1 and RUVBL2 with EP400.NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones.Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC).Involved in the localization of PALB2； BRCA2 and RAD51； but not BRCA1； to DNA-damage foci.
应用： Immunology research
来源： E.coli

其它标识

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

产品介绍 Product Introduction

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