Recombin human HISPPD1 protein,BR

基因名:HISPPD1
英文全称:histidine acid phosphatase domain containing 1
别称:Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2;Diphosphoinositol pentakisphosphate kinase 2;Histidine acid phosphatase domain-containing protein 1;InsP6 and PP-IP5 kinase 2;VIP1 homolog 2;hsVIP2;HISPPD1;KIAA0433;VIP2;
中文名称:组氨酸酸性磷酸酶结构域蛋白1
Uniprot:O43314
GeneID:23262
交叉反应(推测):Human Mouse (Orangutan)
氨基酸大小:38kDa
表达氨基酸:873-1223aa
Background:Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4 (PubMed:17690096, PubMed:17702752, PubMed:21222653, PubMed:29590114). PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation (PubMed:17690096, PubMed:17702752, PubMed:21222653, PubMed:29590114). Phosphorylates inositol hexakisphosphate (InsP6) at positions 1 or 3 to produce PP-InsP5 which is in turn phosphorylated by IP6Ks to produce (PP)2-InsP4 (PubMed:17690096, PubMed:17702752). Alternatively, phosphorylates at position 1 or 3 PP-InsP5, produced by IP6Ks from InsP6, to produce (PP)2-InsP4 (PubMed:17690096, PubMed:17702752). Required for normal hearing (PubMed:29590114).
Application:Immunology research?
Derived from:E.coli
Purification:NI-NTA affinity purification
Formulation:Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.222.
Shipping:The product is shipped at -242°C temperature. Upon receipt, store it immediately at the temperature listed below.
Storage:Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°c="" for="" 2-225="">
Reconstitution:Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Purity:Purity≥85% as determined by reducing SDS-PAGE.
Endotoxin:/
规格:10ug, 50ug, 100ug, 1mg, 注意：
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