SB-216763游离态一种有效、选择性和ATP竞争性的GSK-3抑制剂,抑制GSK-3α和GSK-3β的 IC50为34.3nM。SB-216763 is a glycogen synthase kinase-3 (GSK3) inhibitor, which can maintain mouse embryonic stem cells (mESCs) in a pluripotent state in the absence of exogenous leukemia inhibitory fact