脱氧核糖核酸酶用于生化研究,临床上常用作祛痰药,也可局部用于脓肿、血肿以及鞘内注射治疗脑膜炎。;用于从蛋白样品中去除DNA
Deoxyribonuclease I from bovine pancreas has been used in a study to investigate a two-dimensional zymogram analysis of nucleases in Bacillus subtilis. Deoxyribonuclease I from bovine pancreas has also been used in a study to investigate the effects of minor and major groove-binding drugs and intercalators on the DNA association of minor groove-binding proteins RecA and deoxyribonuclease I.;一种核酸内切酶,它作用于磷酸二脂键,特别针对毗邻嘧啶核苷的键,从而产生3'末端带自由羟基和5'末端带磷酸盐的多聚核苷酸。酶作用的最佳pH值为7.8。DNA酶能被二价金属活化,被鳌合物如EDTA和十二烷基硫酸钠抑制。浓度为5mM的钙离子可作为稳定剂,以保护DNA酶不被水解酶分解。主要用于用于降解RNA中的DNA,纯化RNA,研究DNA与蛋白质的相互作用。