Recombinant Human IL-1F3/IL-1Ra,BR

产品属性 Product Attributes

基本信息

别名： Interleukin-1 Receptor Antagonist Protein;IL-1RN;IL-1ra;IRAP;ICIL-1RA;IL1 Inhibitor;Anakinra;IL1RN;IL1F3;IL1RA
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 50mM TrisHCl, 200mM NaCl, pH 7.5.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： The product is shipped at ambient temperature.

产品信息

背景说明： Interleukin-1 Receptor Antagonist (IL-1RN) is a member of the IL-1 family.Endogenous IL-1RN is produced in numerous animal disease models as well as in human autoimmune and chronic inflammatory diseases.It binds to IL-1 receptors in competition with IL-1，but does not elicit intracellular response from this binding.Its role in counteracting the proinflammatory effects of IL-1 is being studied by numerous research groups.IL-4 and IL-13 have been shown to amplify the stimulatory effect of IL1-beta on the production of soluble and intracellular forms of IL-1RN.The regulated expression of IL-1RN in various cell types has been shown to be influenced by cytokines.In synovial fibroblasts，IL-1，TNF-alpha，or PDGF markedly enhances the synthesis of IL-1RN.
来源： E.coli

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.

产品介绍 Product Introduction

Recombinant Human Interleukin-1 Receptor Antagonist Protein is produced by our E.coli expression system and the target gene encoding Arg26-Glu177 is expressed.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。