Recombinant Human uPAR/CD87,BR

产品属性 Product Attributes

基本信息

别名： Urokinase Plasminogen Activator Surface Receptor;U-PAR;uPAR;Monocyte activation antigen Mo3;CD87;PLAUR;MO3;UPAR
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20℃ for 3 months.
运输条件： The product is shipped at ambient temperature.

产品信息

背景说明： The Urokinase Type Plasminogen Activator (uPA) receptor (uPAR) is a widely expressed receptor for urokinase plasminogen activator (uPA) and pro-uPA.uPAR / CD87 is a highly glycosylated，55-60kDa integral membrane protein linked to the plasma membrane by a glycosylphosphatidylinositol (GPI) anchor.uPAR is expressed by T-cells，NK cells，monocytes，and neutrophils as well as non-hematopoietic cells that include vascular endothelial cells，fibroblasts，smooth muscle cells，keratinocytes，placental trophoblasts，hepatocytes，and a wide variety of tumor cells (including breast，colon，and prostate carcinoma，melanoma).It plays a critical role in the regulation of cell-surface plasminogen activation in physiological and pathological conditions，and it is also involved in cellular adhesion，the transmission of extracellular signals across the plasma membrane and the subsequent regulation of gene expression.uPAR has been implicated in several biological processes including angiogenesis，monocyte migration，cancer metastasis，trophoblast implantation，and wound healing.Human uPAR is encoded as a 313 amino acid residue polypeptide，excluding a 22 residue signal peptide and shows 60-70% similarity with the murine uPAR amino acid sequence although binding of uPA to uPAR shows strong species specificity.
来源： Human cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.

产品介绍 Product Introduction

Recombinant Human Urokinase Plasminogen Activator Surface Receptor is produced by our Mammalian expression system and the target gene encoding Leu23-Arg303 is expressed with a 6His tag at the C-terminus.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。