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Anti-DKK1 Polyclonal Antibody,BR
Anti-DKK1 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-DKK1 Polyclonal Antibody中文名称: Dickkopf相关蛋白1抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Dog预测
交叉反应:: Human;Mouse;Rat
应用: ELISA ; IF ; IHC
稀释比例: ELISA 1:5000-10000. IHC 1:100-500. IF 1:100-500.
抗体信息
靶标: DKK1别名: DKK-1,SK,Dickkopf-related protein 1,Dickkopf-1,hDkk-1,UNQ492/PRO1008,Dickkopf 1 ,DKK 1,DKK1_HUMAN,Dickkopf 1 homolog
背景说明: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Swiss Prot: O94907
Gene ID: 22943
亚细胞定位: Secreted
免疫原: A synthetic peptide of human DKK1
Public Immunogen Range: 201-266/266aa
理论分子量: 29kDa
其它标识
纯化方法: Affinity purification储存液: 0.01M TBS(pH7.4) with 1% BSA,0.03% Proclin300 and 50% Glycerol.
储存条件: Store at -20℃. Avoid freeze / thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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