Recombinant Human UBE2K/Ubiquitin-conjugating enzyme E2 K/E2-25K,BR

产品属性 Product Attributes

基本信息

别名： Ubiquitin-Conjugating Enzyme E2 K;Huntingtin-Interacting Protein 2;HIP-2;Ubiquitin Carrier Protein;Ubiquitin-Conjugating Enzyme E2-25 kDa;Ubiquitin-Conjugating Enzyme E2(25K);Ubiquitin-Conjugating Enzyme E2-25K;Ubiquitin-Protein Ligase;UBE2K;HIP2;LIG
中文名称: Recombinant Human UBE2K/Ubiquitin-conjugating enzyme E2 K/E2-25K
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Ubiquitin-Conjugating Enzyme E2 K (UBE2K) belongs to the E2 Ubiquitin-Conjugating Enzyme family.UBE2K is highly expressed in the brain，with highest levels found in cortex and striatum，and at lower levels in cerebellum and brainstem.UBE2K may mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53.UBE2K is associated with the selective degradation of short-lived and abnormal proteins，such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins.In addition，UBE2K is involved in Alzheimer's disease，Huntington's disease and antigen processing through its interaction with huntingtin，and MHC-heavy chain proteins.
来源： E.coli

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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