Recombinant Mouse ALK-1/Activin Receptor-like Kinase 1/ACVRL1,BR

产品属性 Product Attributes

基本信息

别名： Serine/threonine-protein kinase receptor R3;SKR3;Activin receptor-like kinase 1;ALK-1;TGF-B superfamily receptor type I;TSR-I;ACVRL1;activin A receptor type II-like 1;activin A receptor
中文名称: Recombinant Mouse ALK-1/Activin Receptor-like Kinase 1/ACVRL1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-β superfamily of ligands，which mediates signaling of BMP9 (bone morphogenetic protein) and BMP10.ALK1 signaling is necessary for angiogenesis during embryogenesis，wound healing，and tumor growth.ALK-1 has a high degree of similarity in serine-threonine kinase subdomains，a glycine and serine rich region preceding the kinase-domain，and a C-terminal tail with other activin receptor-like kinase proteins.ALK-1 is mainly expressed in endothelial cells regulating proliferation and migration in vitro and angiogenesis in vivo.Mutations in ALK-1 as well as in endoglin are associated with hereditary hemorrhagic telangiectasia (HHT)，suggesting ALK-1 plays a critical role for in the control of blood vessel development or repair.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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