Recombinant Human TSLP R/CRLF2 (C-Fc),BR

产品属性 Product Attributes

基本信息

别名： CRL2;CRL2cytokine receptor CRL2 precusor;CRLF2;CRLF2Y;CRLM-2;Cytokine receptor-like 2;cytokine receptor-like factor 2;ILXR;IL-XR;P2RY8/CRLF2 fusion;PCOR1;TSLP R;TSLP receptor;TSLPR
中文名称: Recombinant Human TSLP R/CRLF2 (C-Fc)
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Receptor for thymic stromal lymphopoietin (TSLP).Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5.Also activates JAK2 (By similarity).Implicated in the development of the hematopoietic system.TSLP R expression is ubiquitous in the immune and hematopoietic cells，but is up-regulated in Th2-skewed cells.Cells expressing TSLP R alone bind TSLP with low affinity.Co-expression of TSLP R and IL-7 R alpha is required for high-affinity TSLP binding and signal transduction.The TSLP R and IL-7 R alpha are coexpressed primarily on monocytes and dendritic cells and at lower levels in lymphoid cells.TSLP has been shown to induce the release of T cell-attracting chemokines from monocytes and enhance the maturation of CD11c+ dendritic cells.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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