Recombinant Human P-selectin Glycoprotein Ligand 1/PSGL-1/CD162,BR

产品属性 Product Attributes

基本信息

别名： P-selectin glycoprotein ligand 1;PSGL-1;Selectin P ligand;CD162;SELPLG
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,pH8.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： PSGL-1 (CD162)，is a mucintype glycoprotein that plays a key role in leukocyte adhesion.Human PSGL-1 cDNA encodes 412 amino acids (aa).It expressed on neutrophils，monocytes and most lymphocytes.The mature PSGL-1 (aa 42-412) is expressed as a disulfide-linked homodimer that signals intracellularly and promotes integrin activation.PSGL-1 is found on virtually all leukocytes，dendritic cells，platelets，and some endothelial cells.It is primarily responsible for early events in extravasation，especially rolling adhesion of leukocytes to vascular endothelium.Through high affinity，This SLe(x)-type proteoglycanPGSL-1 calcium-dependent interactions with E-，P- and L-selectins，mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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