Recombinant Mouse ALCAM/CD166,BR

产品属性 Product Attributes

基本信息

别名： CD166 antigen;cluster of differentiation 166;CD166;activated leucocyte cell adhesion molecule;CD6 ligand;Protein DM-GRASP;CD6L;MEMD
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Activated leukocyte cell adhesion molecule (ALCAM)，also named as CD166 and MEMD，is a typeI transmembrane glycoprotein of immunoglobulin superfamily，which mediates homotypic and heterotypic interactions between cells.ALCAM interacts with high affinity with CD6 molecule but weaker homotypic (ALCAM–ALCAM) interactions have also been described.ALCAM–CD6 interactions play an important role in the maintenance of T cell activation，proliferation as well as in formation of immune synapse between antigen-presenting cell and lymphocytes.ALCAM is expressed on a wide variety of cells，particularly on activated lymphocytes，dendritic cells and monocytes，and on various epithelial cell types.It is also involved in multiple processes including embryogenesis，hematopoiesis，angiogenesis，and immune response.While expressed in a wide variety of tissues，ALCAM is usually restricted to subsets of cells in most adult tissues.Recently studies showed ALCAM has prognostic relevance in several human carcinomas，and it has been used as a biomarker for several tumor entities，including melanoma，gynecologic，urologic，and gastrointestinal cancers.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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