Recombinant Mouse OX40/TNFRSF4/CD134,BR

产品属性 Product Attributes

基本信息

别名： Tumor necrosis factor receptor superfamily member 4;Tnfrsf4;OX40;CD134;Txgp1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： OX40，also termed CD134 and TNFRSF4，is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells.OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7.The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs).The T-cell functions，including cytokine production，expansion，and survival，are then enhanced by the OX40 costimulatory signals.OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells.OX40-OX40L interaction regulates T-cell tolerance，peripheral T-cell homeostasis，and T-cell-mediated inflammatory diseases.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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注意事项 Considerations

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