Recombinant Mouse CD266/TNFRSF12A/Fn14/TWEAKR,BR

产品属性 Product Attributes

基本信息

别名： Tumor necrosis factor receptor superfamily member 12A;Fibroblast growth factor-inducible immediate-early response protein 14;Fibroblast growth factor-regulated protein 2;Tweak-receptor;TweakR;TNFRSF12
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Tumor necrosis factor receptor superfamily member 12A(Tnfrsf12a) is a single-pass type I membrane protein and contains 1 TNFR-Cys repeat.It is weak inducer of apoptosis in some cell types.It promotes angiogenesis and it is the proliferation of endothelial cells.It may modulate cellular adhesion to matrix proteins.TNFR binds specifically to tumor necrosis factor (TNF) and blocks its interaction with cell surface TNF receptors.TNF is a naturally occurring cytokine that is involved in normal inflammatory and immune responses.It plays an important role in the inflammatory processes of rheumatoid arthritis (RA)，polyarticular-course juvenile rheumatoid arthritis (JRA)，and ankylosing spondylitis and the resulting joint pathology.In addition，TNF plays a role in the inflammatory process of plaque psoriasis.Elevated levels of TNF are found in involved tissues and fluids of patients with RA，psoriatic arthritis，ankylosing spondylitis (AS)，and plaque psoriasis.Two distinct receptors for TNF (TNFRs)，a 55 kilodalton protein (p55) and a 75 kilodalton protein (p75)，exist naturally as monomeric molecules on cell surfaces and in soluble forms.Biological activity of TNF is dependent upon binding to either cell surface TNFR.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。