Recombin human KIR2DL3 protein,BR

产品属性 Product Attributes

基本信息

基因名: KIR2DL3
别名: KIR2DL3;CD158B2;CD158b;GL183;KIR-023GB;KIR-K7b;KIR-K7c;KIR2DS5;KIRCL23;NKAT;NKAT2;NKAT2A;NKAT2B;p58;killer cell immunoglobulin-like receptor 2DL3
全名: killer cell immunoglobulin-like receptor，two domains，long cytoplasmic tail，3
英文名称: Recombinant human KIR2DL3 protein
中文名称: 杀伤细胞免疫球蛋白样受体2DL3
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Liquid: Supplied as a 0.2 μm filtered solution of 20mM Tris, 0.5M NaCl, 10% Gly, pH8.0.
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at < -70°C for 6 months.Please minimize freeze-thaw cycles.
运输条件: The product is shipped on dry ice.Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

产品信息

Swiss Prot： P43628
Gene ID： 3804
交叉反应： Human
分子量： 24kDa
区间范围： 22-242aa
背景说明： Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells.The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC).The gene content of the KIR gene cluster varies among haplotypes, although several framework genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2).The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain.KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals.The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.
应用： Immunology research
来源： E.coli

其它标识

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

产品介绍 Product Introduction

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