Anti-UMOD Polyclonal Antibody,BR
Anti-UMOD Polyclonal Antibody
(订货以英文名为准)
Anti-UMOD Polyclonal Antibody
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英文名称:Anti-UMOD Polyclonal Antibody
宿主:Rabbit
别名:ADMCKD2;FJHN;HNFJ;HNFJ1;MCKD2;THGP;THP
交叉反应:Human Mouse
应用:WB
稀释比例:WB 1:500-2000.
蛋白分子量:70kDa
Gene ID:7369
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG
免疫原:Recombinant protein of human UMOD
性状:液体
亚细胞定位:Apical cell membrane Basolateral cell membrane Cell projection GPI-anchor Lipid-anchor Secreted cilium membrane
Swiss Prot:P07911
背景资料:
The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants.
Public Immunogen Range:Recombinant protein of human UMOD
克隆类型:Polyclonal Antibody
规格:50ul, 100ul,
注意：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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