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- Anti-COPS7B Polyclonal Antibody,BR
Anti-COPS7B Polyclonal Antibody,BR
Anti-COPS7B Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-COPS7B Polyclonal Antibody中文名称: COP9信号小体复合体7B抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human
应用: WB ; IHC
稀释比例: WB 1:1000-3000. IHC 1:50-200.
抗体信息
靶标: COPS7B别名: COP9 Complex Homolog Subunit 7b, COP9 Constitutive Photomorphogenic Homolog Subunit 7b, COP9 Signalasome Subunit 7b, COP9 signalosome complex subunit 7b, COPS7B, CSN7B_HUMAN, JAB1 Containing Signalosome Subunit 7b, JAB1-containing signalosome subunit 7b, SGN7b, Signalosome subunit 7b
背景说明: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
Swiss Prot: Q9H9Q2
Gene ID: 64708
亚细胞定位: Cytoplasm Nucleus
免疫原: Recombinant protein of human COPS7B
Public Immunogen Range: 1-157aa
理论分子量: 18/30/31kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。