Anti-CDK2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CDK2 Polyclonal Antibody
中文名称： 周期蛋白-依赖性蛋白激酶2抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IHC
稀释比例： IHC 1:25-100.

抗体信息

靶标： CDK2
别名： Cdc2 related protein kinase, cdc2-related protein kinase, Cdk 2, CDK2_HUMAN, Cell devision kinase 2, Cell division kinase 2, Cell division protein kinase 2, Cyclin dependent kinase 2, cyclin dependent kinase 2-alpha, Cyclin-dependent kinase 2, p33 protein kinase, p33(CDK2)
背景说明： Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK1 at the centrosome and in the nucleus. Crucial role in orchestrating a fine balance between cellular proliferation, cell death, and DNA repair in human embryonic stem cells (hESCs).
Swiss Prot： P24941
Gene ID： 1017
亚细胞定位： Cytoplasm Nucleus
免疫原： A synthetic peptide of Human CDK2
Public Immunogen Range： 220-270/298aa
理论分子量： 30/34kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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