Recombinant Human SUMO2/Small ubiquitin-related modifier 2,BR

产品属性 Product Attributes

基本信息

别名： Small Ubiquitin-Related Modifier 2;SUMO-2;HSMT3;SMT3 homolog 2;SUMO-3;Sentrin-2;Ubiquitin-Like Protein SMT3A;Smt3A;SUMO2;SMT3A;SMT3H2
中文名称: Recombinant Human SUMO2/Small ubiquitin-related modifier 2
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Small Ubiquitin-Related Modifier 2 (SUMO2) is an Ubiquitin-like protein that belongs to the ubiquitin family with SUMO subfamily.It is a family of small，related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation.SUMO2 can be covalently attached to proteins as a monomer or as a lysine-linked polymer.Covalent attachment via an isopeptidebond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I，and can be promoted by an E3 ligase such as PIAS1-4，RANBP2 or CBX4.This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport，DNA replication and repair，mitosis and signal transduction.Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.
来源： E.coli

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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