Recombinant Human Tie-2/CD202b/TEK/VMCM,BR

产品属性 Product Attributes

基本信息

别名： angiopoietin-1 receptor;CD202b antigen;CD202b;EC 2.7.10;EC 2.7.10.1;hTIE2;p140 TEK;soluble TIE2 variant 1;soluble TIE2 variant 2;TEK tyrosine kinase,endothelial;TEK;Tie2;Tie-2;VMCM;VMCM1
中文名称: Recombinant Human Tie-2/CD202b/TEK/VMCM
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Tie-1/Tie (tyrosine kinase with Ig and EGF homology domains 1) and Tie-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains and followed by three fibronectin type III-like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region.These receptors are expressed primarily on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis，vasculogenesis and hematopoiesis.Human Tie-2 cDNA encodes a 1124 amino acid (aa) residue precursor protein with an 18 residue putative signal peptide，a 727 residue extracellular domain and a 354 residue cytoplasmic domain.Two ligands，angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2)，which bind Tie-2 with high-affinity have been identified.Ang-2 has been reported to act as an antagonist for Ang-1.Mice engineered to overexpress Ang-2 or to lack Ang-1 or Tie-2 display similar angiogenesis defects.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

暂无数据

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。