Recombinant Human TREML1/TLT1/Trem-like transcript 1 protein,BR

产品属性 Product Attributes

基本信息

别名： Trem-Like Transcript 1 Protein;TLT-1;Triggering Receptor Expressed on Myeloid Cells-Like Protein 1;TREML1;TLT1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 (TREML1) is a single-pass type I membrane protein.TREML1 precursor contains a 15 amino acid signal peptide，a 147 amino acid extracellular domain with an Ig-like V-type (immunoglobulin-like) domain，and 128 amino acid cytoplasmic domain.It can be expressed exclusively in platelets and megakaryocytes (MKs).It is a cell surface receptor that may play a role in the innate and adaptive immune response.TREML1 Sequestered in cytoplasmic vesicles in resting platelets.TREML1 be transported to the cell surface after stimulation by thrombin.Soluble fragments can be released into the serum by proteolysis.The phosphorylated TREML1 can interact with PTPN6 and PTPN11.TREML1 may participate in maintaining vascular hemostasis and regulating coagulation and inflammation at sites of injury.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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