Recombinant Mouse Sonic Hedgehog/Shh (C25II),BR

产品属性 Product Attributes

基本信息

别名： Sonic Hedgehog Protein;SHH;HHG-1;SHH
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM DTT, pH 7.4.
纯度: ≥90% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Mouse Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog.The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH).Hedgehog proteins are key signaling molecules in embryonic development.SHH is expressed in various embryonic tissues and plays critical roles in regulating the patterning of many systems，such as limbs and brain.SHH also plays an important role in adult，including the division of adult stem cells and the development of certain cancers and other diseases.Mouse Shh is synthesized as a 437 aa precursor that contains a 24 aa signal sequence and a 413 aa mature region.The mature region is autocatalytically processed into a nonglycosylated，20 kDa，174 aa N-terminal fragment (Shh-N)，and a catalytic-processing，glycosylated，34 kDa，239 aa C-terminal fragment.The 20 kDa Shh-N fragment is the core of the active hedgehog molecule.Mouse Shh-N is 99%，98%，and 100% aa identical to human，rat and gerbil Shh-N，respectively.
来源： E.coli

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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