Recombinant Human IFN-λ2/IL-28A/Interferon Lambda-2,BR

产品属性 Product Attributes

基本信息

别名： Interferon lambda-2;IFN-lambda-2;Cytokine Zcyto20;Interleukin-28A;IL-28A;IFNL2;IL28A;ZCYTO20
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： IL-28A (Interferon-λ2 IFN-λ2)，IL-28B/IFN-λ3，and IL-29/IFN-λ1 are type III interferons which are distantly related to IL-10 family and type I IFN family cytokines.Mature human IL-28A is an approximately 22-25 kDa protein that shares 66% amino acid (aa) sequence identity with mouse and rat IL-28A and shows cross-species activity.It shares 96% and 70% aa sequence identity with human IL-28B and IL-29，respectively.IL-28A promotes the Th1 polarization of dendritic cells in the airway and inhibits Th2 and Th17 mediated inflammation.IL-28A additionally exhibits anti-tumor activity，in part by enhancing IL-12 dependent anti-tumor CTL responses in vivo.In contrast，it is up-regulated in invasive bladder cancer where it promotes tumor cell migration.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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