Recombinant Human Inosine triphosphate pyrophosphatase/ITPA,BR

产品属性 Product Attributes

基本信息

别名： Inosine Triphosphate Pyrophosphatase;ITPase;Inosine Triphosphatase;Non-Canonical Purine NTP Pyrophosphatase;Non-Standard Purine NTP Pyrophosphatase;Nucleoside-Triphosphate Diphosphatase;Nucleoside-Triphosphate Pyrophosphatase;NTPase;Putative Oncogene Protein hlc14-06-p;ITPA;C20orf37
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, pH 8.0.
纯度: ≥90% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Inosine Triphosphate Pyrophosphatase (ITPase) is a cytoplasmic enzyme that belongs to the HAM1 NTPase family.ITPase hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP) and deoxyinosine triphosphate (dITP) to the monophosphate nucleotide (IMP) and diphosphate.The ITPase enzyme acts as a homodimer and does not distinguish between the deoxy- and ribose forms.ITPase probably excludes non-canonical purines from RNA and DNA precursor pools，thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.Defects in ITPase is thought to be inherited and is characterized by an over-accumulation of ITP in erythocytes，leukocytes and fibroblasts.
来源： E.coli

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

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